Article
EGFR exon 19 in-frame deletion and polymorphisms of DNA repair genes in never-smoking female lung adenocarcinoma patients.
International journal of cancer - 15 Jan 2013
Yang Shi-Yi, Yang Tsung-Ying, Li Yao-Jen, Chen Kun-Chieh, Liao Kuo-Meng, Hsu Kuo-Hsuan, Tsai Chi-Ren, Chen Chih-Yi, Hsu Chung-Ping, Hsia Jiun-Yi, Chuang Cheng-Yen, Tsai Ying-Huang, Chen Kuan-Yu, Huang Ming-Shyan, Su Wu-Chou, Chen Yuh-Min, Hsiung Chao A, Shen Chen-Yang, Chang Gee-Chen, Yang Pan-Chyr, Chen Chien-Jen
Abstract excerpt
We explored potential associations between genetic polymorphisms in genes related to DNA repair and detoxification metabolism and epidermal growth factor receptor (EGFR) mutations in a cohort of 410 never-smoking patients with lung adenocarcinoma. Multivariate-adjusted odds ratios (aORs) and corresponding 95% confidence intervals (CI) of EGFR mutation status in association with the genotypes of DNA repair and...
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