Article
Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer.
International journal of cancer - 1 Oct 2010
Timofeeva Maria, Kropp Silke, Sauter Wiebke, Beckmann Lars, Rosenberger Albert, Illig Thomas, Jäger Birgit, Mittelstrass Kirstin, Dienemann Hendrik, Bartsch Helmut, Bickeböller Heike, Chang-Claude Jenny, Risch Angela, Wichmann Heinz-Erich
Abstract excerpt
Early-onset lung cancer diagnosed up to the age of 50 is a very rare disease, with an increasing incidence rate. Differences in aetiology, characteristics and epidemiology of early and older onset lung cancer have been described previously, suggesting the importance of genetic factors in early-onset lung cancer aetiology. A case-control study was conducted to investigate the effects of genetic polymorphisms in...
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