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Article

Single nucleotide polymorphisms in the NER pathway and clinical outcome of patients with bone malignant tumors.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Sun Xiao-Hui, Hou Wen-Gen, Zhao Hong-Xing, Zhao Yi-Lei, Ma Chao, Liu Ying

Abstract excerpt

The effects of polymorphisms in ERCC5, ERCC6, XPC, CCNH and MMS19L on osteosarcoma response to chemotherapy and the survival of the affected patients were assessed. Genotyping of ERCC5, ERCC6, XPC, CCNH and MMS19L was performed by PCR-RFLP assay. The median PFS was 12.8 months, and the median OS was 18.6 months. Individuals carrying homozygous genotypes of ERCC5 rs17655 and ERCC5 rs1047768 were more like to have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23679317
DOI: 10.7314/apjcp.2013.14.3.2049

Genes

ERCC5
CCNH
ERCC6
XPC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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