Article
Formation of intestinal atresias in the Fgfr2IIIb-/- mice is not associated with defects in notochord development or alterations in Shh expression.
The Journal of surgical research - 1 Sept 2012
Reeder Amy L, Botham Robert A, Franco Marta, Zaremba Krzysztof M, Nichol Peter F
Abstract excerpt
PURPOSE: The etiology of intestinal atresia remains elusive but has been ascribed to a number of possible events including in utero vascular accidents, failure of recanalization of the intestinal lumen, and mechanical compression. Another such event that has been postulated to be a cause in atresia formation is disruption in notochord development. This hypothesis arose from clinical observations of notochord...
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