Article
A genetic mechanism for cecal atresia: the role of the Fgf10 signaling pathway.
The Journal of surgical research - 1 Aug 2004
Fairbanks T J, Kanard R C, De Langhe S P, Sala F G, Del Moral P M, Warburton D, Anderson K D, Bellusci S, Burns R C
Abstract excerpt
BACKGROUND: Intestinal atresia represents a significant surgically correctable cause of intestinal obstruction in neonates. Intestinal development proceeds as a tube-like structure with differentiation along its axis. As the intestine differentiates, the cecum develops at the transition from small to large intestine. Fgf10 is known to serve a key role in budding morphogenesis; however, little is known about its...
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