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Article

Hedgehog Signaling in Development and Homeostasis of the Gastrointestinal Tract

1 Oct 2007

Abstract excerpt

The Hedgehog family of secreted morphogenetic proteins acts through a complex evolutionary conserved signaling pathway to regulate patterning events during development and in the adult organism. In this review I discuss the role of Hedgehog signaling in the development, postnatal maintenance, and carcinogenesis of the gastrointestinal tract. Three mammalian hedgehog genes, sonic hedgehog (Shh), indian hedgehog...

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PMID: 17928586
DOI: 10.1152/physrev.00054.2006

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