Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis.

Developmental biology - 1 Jul 2014

Fausett Sarah R, Brunet Lisa J, Klingensmith John

Abstract excerpt

Esophageal atresia with tracheoesophageal fistula (EA/TEF) is a serious human birth defect, in which the esophagus ends before reaching the stomach, and is aberrantly connected with the trachea. Several mouse models of EA/TEF have recently demonstrated that proper dorsal/ventral (D/V) patterning of the primitive anterior foregut endoderm is essential for correct compartmentalization of the trachea and esophagus....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Patterning
Share to Bone Morphogenetic Proteins
Share to Cell Death

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophagus

Share to Hedgehog Proteins

Share to In Situ Hybridization

Share to Notochord

Share to Trachea

Source

Identifiers

PMID: 24631216
DOI: 10.1016/j.ydbio.2014.02.008

Genes

TEF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BMP antagonism by Noggin is required in presumptive notochord cells for mammalian foregut morphogenesis.PMID 24631216Read ↗

Aberrant Bmp signaling and notochord delamination in the pathogenesis of esophageal atresiaSemantic proximity Read ↗

Defects in tracheoesophageal and lung morphogenesis in Nkx2.1(-/-) mouse embryos.Semantic proximity Read ↗

Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog-Gli Is Required for Tracheoesophageal Separation.Semantic proximity Read ↗

Endosome-Mediated Epithelial Remodeling Downstream of Hedgehog/Gli Is Required for Tracheoesophageal SeparationSemantic proximity Read ↗

Genetic and cellular mechanisms of the formation of esophageal atresia and tracheoesophageal fistula.Semantic proximity Read ↗

Barx1-Mediated Inhibition of Wnt Signaling in the Mouse Thoracic Foregut Controls Tracheo-Esophageal Septation and Epithelial DifferentiationSemantic proximity Read ↗

The initial establishment and epithelial morphogenesis of the esophagus: a new model of tracheal–esophageal separation and transition of simple columnar into stratified squamous epithelium in the developing esophagusSemantic proximity Read ↗

Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in trachea-esophageal morphogenesisSemantic proximity Read ↗

Primary cilia are critical for tracheoesophageal septation.Semantic proximity Read ↗

Cessation of gastrulation is mediated by suppression of epithelial-mesenchymal transition at the ventral ectodermal ridge.Semantic proximity Read ↗

Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in Xenopus trachea-esophageal morphogenesis.Semantic proximity Read ↗

Foregut separation and tracheo-oesophageal malformations: the role of tracheal outgrowth, dorso-ventral patterning and programmed cell death.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.