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Article

The hypoxic epicardial and subepicardial microenvironment.

Journal of cardiovascular translational research - 1 Oct 2012

Kocabas Fatih, Mahmoud Ahmed I, Sosic Drazen, Porrello Enzo R, Chen Rui, Garcia Joseph A, DeBerardinis Ralph J, Sadek Hesham A

Abstract excerpt

Recent reports indicate that the adult mammalian heart is capable of limited, but measurable, cardiomyocyte turnover. While the lineage origin of the newly formed cardiomyocytes is not entirely understood, mounting evidence suggest that the epicardium and subepicardium may represent an important source of cardiac stem or progenitor cells. Stem cell niches are characterized by low oxygen tension, where stem cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22566269
DOI: 10.1007/s12265-012-9366-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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