Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypoxia‐Inducible Factor and the Development of Stem Cells of the Cardiovascular System

1 Jul 2001

Abstract excerpt

Decreased oxygen (O2) levels activate hypoxia-inducible factor (HIF-1) to induce genes involved in glycolysis, glucose transport, erythropoiesis, and angiogenesis. Mutations in various HIF-1 subunits have contributed to our understanding of the role hypoxia plays during early embryonic development in general and the cardiovascular system in particular. We propose that HIF-1 is important for the generation,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Congenital heart defects research
Share to Neonatal Respiratory Health Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11463947
DOI: 10.1634/stemcells.19-4-279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypoxia‐Inducible Factor and the Development of Stem Cells of the Cardiovascular SystemPMID 11463947Read ↗

Regulation of Cardiovascular Development and Physiology by Hypoxia‐Inducible Factor 1<sup>a</sup>Semantic proximity Read ↗

Hypoxia-Induced Signaling in the Cardiovascular SystemSemantic proximity Read ↗

Hypoxia-induced signaling in the cardiovascular system: pathogenesis and therapeutic targetsSemantic proximity Read ↗

The role of oxygen availability in embryonic development and stem cell function.Semantic proximity Read ↗

Oxygen, genes, and development: An analysis of the role of hypoxic gene regulation during murine vascular developmentSemantic proximity Read ↗

Expression of hypoxia-inducible factor 1: mechanisms and consequencesSemantic proximity Read ↗

Hypoxia Promotes Efficient Differentiation of Human Embryonic Stem Cells to Functional EndotheliumSemantic proximity Read ↗

Hypoxia-inducible factor 1-related diseases and prospective therapeutic tools.Semantic proximity Read ↗

HIF-1: mediator of physiological and pathophysiological responses to hypoxiaSemantic proximity Read ↗

Hypoxia signaling in human diseases and therapeutic targetsSemantic proximity Read ↗

Transcriptional Regulation by Hypoxia-Inducible Factor 1 Molecular Mechanisms of Oxygen HomeostasisSemantic proximity Read ↗

Biology of hypoxia-inducible factor-2alpha in development and disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.