Article
Regional mapping of myocardial hibernation phenotype in idiopathic end-stage dilated cardiomyopathy.
Journal of cellular and molecular medicine - 1 Mar 2014
Lionetti Vincenzo, Matteucci Marco, Ribezzo Marco, Di Silvestre Dario, Brambilla Francesca, Agostini Silvia, Mauri Pierluigi, Padeletti Luigi, Pingitore Alessandro, Delsedime Luisa, Rinaldi Mauro, Recchia Fabio A, Pucci Angela
Abstract excerpt
Myocardial hibernation (MH) is a well-known feature of human ischaemic cardiomyopathy (ICM), whereas its presence in human idiopathic dilated cardiomyopathy (DCM) is still controversial. We investigated the histological and molecular features of MH in left ventricle (LV) regions of failing DCM or ICM hearts. We examined failing hearts from DCM (n = 11; 41.9 ± 5.45 years; left ventricle-ejection fraction (LV-EF),...
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