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Article

Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice.

Neuropharmacology - 1 May 2013

Matrisciano Francesco, Tueting Patricia, Dalal Ishani, Kadriu Bashkim, Grayson Dennis R, Davis John M, Nicoletti Ferdinando, Guidotti Alessandro

Abstract excerpt

Human studies suggest that a variety of prenatal stressors are related to high risk for cognitive and behavioral abnormalities associated with psychiatric illness (Markham and Koenig, 2011). Recently, a downregulation in the expression of GABAergic genes (i.e., glutamic acid decarboxylase 67 and reelin) associated with DNA methyltransferase (DNMT) overexpression in GABAergic neurons has been regarded as a...

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Source

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Identifiers

PMID: 22564440
DOI: 10.1016/j.neuropharm.2012.04.013
PMCID: PMC3433586

Genes

DNMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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