Article
Involvement of Epigenetic Modifications of GABAergic Interneurons in Basolateral Amygdala in Anxiety-like Phenotype of Prenatally Stressed Mice.
The international journal of neuropsychopharmacology - 1 Jun 2018
Zhu Chunting, Liang Min, Li Yingchun, Feng Xuejiao, Hong Juan, Zhou Rong
Abstract excerpt
Background: Prenatal stress is considered a risk factor for anxiety disorder. Downregulation in the expression of GABAergic gene, that is, glutamic acid decarboxylase 67, associated with DNA methyltransferase overexpression in GABAergic neurons has been regarded as a characteristic component of anxiety disorder. Prenatal stress has an adverse effect on the development of the basolateral amygdala, which is a key...
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