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Article

Depressive-like phenotype induced by prenatal dexamethasone in mice is reversed by desipramine.

Neuropharmacology - 1 Nov 2017

Conti Mirko, Spulber Stefan, Raciti Marilena, Ceccatelli Sandra

Abstract excerpt

Exposure to prenatal insults has been associated with an increased risk for neuropsychiatric disorders, including depression, but the mechanisms are still poorly understood. Persistent alterations of the HPA axis feedback mechanism as well as adult impaired neurogenesis are believed to play a relevant role in the etiology of depression. In addition, growing evidence points at epigenetic reprogramming as a key...

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PMID: 28916331
DOI: 10.1016/j.neuropharm.2017.09.015

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DISC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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