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Article

Abscisic acid ameliorates the systemic sclerosis fibroblast phenotype in vitro.

Biochemical and biophysical research communications - 25 May 2012

Bruzzone Santina, Battaglia Florinda, Mannino Elena, Parodi Alessia, Fruscione Floriana, Basile Giovanna, Salis Annalisa, Sturla Laura, Negrini Simone, Kalli Francesca, Stringara Silvia, Filaci Gilberto, Zocchi Elena, Fenoglio Daniela

Abstract excerpt

The phytohormone abscisic acid (ABA) has been recently identified as an endogenous hormone in humans, regulating different cell functions, including inflammatory processes, insulin release and glucose uptake. Systemic sclerosis (SSc) is a chronic inflammatory disease resulting in fibrosis of skin and internal organs. In this study, we investigated the effect of exogenous ABA on fibroblasts obtained from healthy...

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PMID: 22560900
DOI: 10.1016/j.bbrc.2012.04.107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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