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Article

Autoantibodies to fibroblasts induce a proadhesive and proinflammatory fibroblast phenotype in patients with systemic sclerosis.

Arthritis and rheumatism - 1 Jun 2002

Chizzolini Carlo, Raschi Elena, Rezzonico Roger, Testoni Cinzia, Mallone Roberto, Gabrielli Armando, Facchini Andrea, Del Papa Nicoletta, Borghi Maria Orietta, Dayer Jean Michel, Meroni Pier Luigi

Abstract excerpt

OBJECTIVE: Fibroblasts play a major role in the development of systemic sclerosis (SSc), and the occurrence of serum autoantibodies reacting with fibroblast plasma membrane antigens in SSc has been reported. This study was undertaken to investigate whether IgG from SSc sera that react with human fibroblasts modulates the fibroblasts' function. METHODS: Sera from 69 patients with SSc (28 with limited cutaneous SSc...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12115192
DOI: 10.1002/art.10361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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