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Article

Myogenesis in dysferlin-deficient myoblasts is inhibited by an intrinsic inflammatory response.

Neuromuscular disorders : NMD - 1 Jul 2012

Cohen Tatiana V, Cohen Jonathan E, Partridge Terence A

Abstract excerpt

Limb-girdle muscular dystrophy type 2B results from mutations in dysferlin, a membrane-associated protein involved in cellular membrane repair. Primary myoblast cultures derived from dysferlinopathy patients show reduced myogenic potential, suggesting that dysferlin may regulate myotube fusion and be required for muscle regeneration. These observations contrast with the findings that muscle develops normally in...

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Identifiers

PMID: 22560623
DOI: 10.1016/j.nmd.2012.03.002
PMCID: PMC4147957

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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