Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B

3 Jun 2019

Abstract excerpt

Muscle loss due to fibrotic or adipogenic replacement of myofibers is common in muscle diseases and muscle-resident fibro/adipogenic precursors (FAPs) are implicated in this process. While FAP-mediated muscle fibrosis is widely studied in muscle diseases, the role of FAPs in adipogenic muscle loss is not well understood. Adipogenic muscle loss is a feature of limb girdle muscular dystrophy 2B (LGMD2B) - a disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Muscle Physiology and Disorders
Share to Neurogenetic and Muscular Disorders Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31160583
DOI: 10.1038/s41467-019-10438-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2BPMID 31160583Read ↗

Signaling pathways regulating the fate of fibro/adipogenic progenitors (FAPs) in skeletal muscle regeneration and diseaseSemantic proximity Read ↗

DAB2 as a biomarker and mechanistic link between lipid dysregulation and disease progression in LGMD R2Semantic proximity Read ↗

Intracellular Membrane Repair Dysregulation and Accumulation of Mature Myostatin Protein are Novel Markers of Muscle Pathophysiology in Pompe DiseaseSemantic proximity Read ↗

Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing.Semantic proximity Read ↗

A guide to examining intramuscular fat formation and its cellular origin in skeletal muscleSemantic proximity Read ↗

Dysferlin and Animal Models for DysferlinopathySemantic proximity Read ↗

Origins, potency, and heterogeneity of skeletal muscle fibro-adipogenic progenitors—time for new definitionsSemantic proximity Read ↗

Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesisSemantic proximity Read ↗

FAP Beige Adipogenesis in Volumetric Muscle LossSemantic proximity Read ↗

Aberrant Fibro-Adipogenic Progenitor Subpopulations Drive Volumetric Muscle Loss-Induced FibrosisSemantic proximity Read ↗

Myogenesis in dysferlin-deficient myoblasts is inhibited by an intrinsic inflammatory response.Semantic proximity Read ↗

Muscle fibro-adipogenic progenitors from a single-cell perspective: Focus on their “virtual” secretomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.