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Article

The effects of MyD88 deficiency on disease phenotype in dysferlin-deficient A/J mice: role of endogenous TLR ligands.

The Journal of pathology - 1 Oct 2013

Uaesoontrachoon Kitipong, Cha Hee-Jae, Ampong Beryl, Sali Arpana, Vandermeulen Jack, Wei Benjamin, Creeden Brittany, Huynh Tony, Quinn James, Tatem Kathleen, Rayavarapu Sree, Hoffman Eric P, Nagaraju Kanneboyina

Abstract excerpt

An absence of dysferlin leads to activation of innate immune receptors such as Toll-like receptors (TLRs) and skeletal muscle inflammation. Myeloid differentiation primary response gene 88 (MyD88) is a key mediator of TLR-dependent innate immune signalling. We hypothesized that endogenous TLR lig...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23857504
DOI: 10.1002/path.4207
PMCID: PMC4071457

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23857504-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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