Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Attenuated muscle regeneration is a key factor in dysferlin-deficient muscular dystrophy

13 Mar 2009

Abstract excerpt

Skeletal muscle requires an efficient and active membrane repair system to overcome the rigours of frequent contraction. Dysferlin is a component of that system and absence of dysferlin causes muscular dystrophy (dysferlinopathy) characterized by adult onset muscle weakness, high serum creatine kinase levels and a prominent inflammatory infiltrate. We have observed that dysferlinopathy patient biopsies show an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exercise and Physiological Responses
Share to Muscle Physiology and Disorders
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19286669
DOI: 10.1093/hmg/ddp121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Attenuated muscle regeneration is a key factor in dysferlin-deficient muscular dystrophyPMID 19286669Read ↗

Myogenesis in dysferlin-deficient myoblasts is inhibited by an intrinsic inflammatory response.Semantic proximity Read ↗

Genetic ablation of complement C3 attenuates muscle pathology in dysferlin-deficient miceSemantic proximity Read ↗

Dysferlin and Animal Models for DysferlinopathySemantic proximity Read ↗

Muscular dystrophy in dysferlin-deficient mouse models.Semantic proximity Read ↗

Dysferlin function in skeletal muscle: Possible pathological mechanisms and therapeutical targets in dysferlinopathies.Semantic proximity Read ↗

Muscle Cells Fix Breaches by Orchestrating a Membrane Repair Ballet.Semantic proximity Read ↗

Dysferlinopathy Promotes an Intramuscle Expansion of Macrophages with a Cyto-Destructive Phenotype.Semantic proximity Read ↗

The effects of MyD88 deficiency on disease phenotype in dysferlin-deficient A/J mice: role of endogenous TLR ligands.Semantic proximity Read ↗

Muscle inflammation and MHC class I up-regulation in muscular dystrophy with lack of dysferlin: an immunopathological studySemantic proximity Read ↗

In Vivo and In Vitro Dysferlin Expression in Human Muscle Satellite CellsSemantic proximity Read ↗

“The Social Network” and Muscular Dystrophies: The Lesson Learnt about the Niche Environment as a Target for Therapeutic StrategiesSemantic proximity Read ↗

Absence of Dysferlin Alters Myogenin Expression and Delays Human Muscle Differentiation “in Vitro”Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.