Article
Absence of Dysferlin Alters Myogenin Expression and Delays Human Muscle Differentiation “in Vitro”
11 Apr 2006
Abstract excerpt
Mutations in dysferlin cause a type of muscular dystrophy known as dysferlinopathy. Dysferlin may be involved in muscle repair and differentiation. We compared normal human skeletal muscle cultures expressing dysferlin with muscle cultures from dysferlinopathy patients. We quantified the fusion index of myoblasts as a measure of muscle development and conducted optic and electronic microscopy, immunofluorescence,...
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