Article
Patients with unstable angina pectoris show an increased frequency of the Fc gamma RIIa R131 allele.
Autoimmunity - 1 Nov 2012
Raaz-Schrauder Dorette, Ekici Arif B, Munoz Luis E, Klinghammer Lutz, Voll Reinhard E, Leusen Jeanette H W, van de Winkel Jan G J, Reis André, Schett Georg, Garlichs Christoph D, Herrmann Martin
Abstract excerpt
Patients with Systemic Lupus Erythematosus (SLE) carry an increased risk for the development of coronary artery disease (CAD). The R131 allele of the Fc gamma receptor IIa (FcγRIIa) is associated with SLE incidence and disease severity but also with CAD. Compared to stable angina pectoris (SAP) the unstable angina (UAP), as a manifestation of destabilizing CAD, is associated with increased risk of persistent...
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