Article
FcgammaRIIa polymorphism in Japanese patients with systemic lupus erythematosus.
Lupus - 1 Jan 2001
Sato H, Iwano M, Akai Y, Nishino T, Fujimoto T, Shiiki H, Dohi K
Abstract excerpt
Systemic lupus erythematosus (SLE) is an immune complex-mediated disease and organ damage is caused by the deposition of immune complex. Receptors which recognize the Fc portion of immunoglobulin G (FcgammaR) play a key role in the phagocytosis of immune complexes. As the gene encoding for Fcgamm...
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