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Article

The Fcγ receptor IIA R131H gene polymorphism is associated with endothelial function in patients with hypercholesterolaemia.

Atherosclerosis - 1 Oct 2011

Schneider Markus P, Leusen Jeanette H W, Herrmann Martin, Garlichs Christoph D, Amann Kerstin, John Stefan, Schmieder Roland E

Abstract excerpt

OBJECTIVE: A gene polymorphism substituting arginine (R) for histidine (H) at position 131 has been described within the Fcγ receptor IIa (FcγRIIa). The R allele is associated with increased binding of CRP and enhanced activation of monocytes. FcγRIIa is also expressed on endothelial cells, and we hypothesized this polymorphism would be associated with alterations of endothelial function. METHODS: Genomic DNA was...

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PMID: 21813128
DOI: 10.1016/j.atherosclerosis.2011.07.009

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CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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