Article
Genetic variation in Fc gamma receptor IIa and risk of coronary heart disease: negative results from two large independent populations.
BMC medical genetics - 29 May 2009
Karakas Mahir, Hoffmann Michael M, Vollmert Caren, Rothenbacher Dietrich, Meisinger Christa, Winkelmann Bernhard, Khuseyinova Natalie, Böhm Bernhard O, Illig Thomas, März Winfried, Koenig Wolfgang
Abstract excerpt
BACKGROUND: The role of the Fc gamma receptor IIa (Fc gamma RIIa), a receptor for C-reactive protein (CRP), the classical acute phase protein, in atherosclerosis is not yet clear. We sought to investigate the association of Fc gamma RIIa genotype with risk of coronary heart disease (CHD) in two large population-based samples. METHODS: Fc gamma RIIa-R/H131 polymorphisms were determined in a population of 527...
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