Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The association between a common FCGR2A polymorphism and C-reactive protein and coronary artery disease revisited.

Genetic testing and molecular biomarkers - 1 Dec 2010

Kroupis Christos, Theodorou Maria, Chaidaroglou Antigoni, Dalamaga Maria, Oliveira Samantha C, Cokkinos Dennis V, Degiannis Dimitrios, Manginas Athanassios

Abstract excerpt

INTRODUCTION: the FcγRIIa receptor is responsible for the clearance of large immune complexes and recently has been proved to be a C-reactive protein (CRP) receptor as well. A polymorphism in the corresponding FCG2RA gene resulting in an amino acid change (R131H) has been implicated, with conflic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to C-Reactive Protein
Share to Coronary Angiography

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Artery Disease

Share to Greece

Share to Polymerase Chain Reaction

Share to Receptors, IgG

Share to Reference Standards

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 20973705
DOI: 10.1089/gtmb.2010.0108

Genes

CAD
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20973705-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association between a common FCGR2A polymorphism and C-reactive protein and coronary artery disease revisited.PMID 20973705Read ↗

Genetic variation in Fc gamma receptor IIa and risk of coronary heart disease: negative results from two large independent populations.Semantic proximity Read ↗

FcgammaRIIa genotype is associated with acute coronary syndromes as first manifestation of coronary artery disease.Semantic proximity Read ↗

C-reactive protein binding to FcgammaRIIa on human monocytes and neutrophils is allele-specific.Semantic proximity Read ↗

The proinflammatory effect of C-reactive protein on human endothelial cells depends on the FcγRIIa genotype.Semantic proximity Read ↗

Fcgamma receptor IIIA polymorphism as a risk-factor for coronary artery disease.Semantic proximity Read ↗

C-reactive protein gene polymorphisms affect plasma CRP and homocysteine concentrations in subjects with and without angiographically confirmed coronary artery disease.Semantic proximity Read ↗

C-reactive protein triggers calcium signalling in human neutrophilic granulocytes via FcγRIIa in an allele-specific way.Semantic proximity Read ↗

Genetic Association Studies Reporting on Variants in the C-Reactive Protein Gene and Coronary Artery Disease: A Meta-Analysis.Semantic proximity Read ↗

The Fcγ receptor IIA R131H gene polymorphism is associated with endothelial function in patients with hypercholesterolaemia.Semantic proximity Read ↗

Genetic variation in Fcgamma receptor IIa protects against advanced peripheral atherosclerosis. The Rotterdam Study.Semantic proximity Read ↗

Impact of CD14 Polymorphisms on Anti-Apolipoprotein A-1 IgG-Related Coronary Artery Disease Prediction in the General Population.Semantic proximity Read ↗

FC gamma RIIa polymorphism in patients with rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.