Article
FcgammaRIIa genotype is associated with acute coronary syndromes as first manifestation of coronary artery disease.
Atherosclerosis - 1 Aug 2009
Raaz Dorette, Herrmann Martin, Ekici Arif B, Klinghammer Lutz, Lausen Berthold, Voll Reinhard E, Leusen Jeanette H W, van de Winkel Jan G J, Daniel Werner G, Reis André, Garlichs Christoph D
Abstract excerpt
OBJECTIVE: Identification of clinically relevant determinants for acute coronary syndromes (ACS) promises reduction of ACS-associated mortality. C-reactive protein (CRP) has proved to be useful identifying people at risk for cardiovascular events. However, it is unknown whether genetic variants at Fcgamma receptor IIa (FcgammaRIIa), the main receptor for CRP, are involved in CRP-related cardiovascular risk. We...
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