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Article

Impact of treadmill running and sex on hippocampal neurogenesis in the mouse model of amyotrophic lateral sclerosis.

PloS one - 1 Jan 2012

Ma Xiaoxing, Hamadeh Mazen J, Christie Brain R, Foster Jane A, Tarnopolsky Mark A

Abstract excerpt

Hippocampal neurogenesis in the subgranular zone (SGZ) of dentate gyrus (DG) occurs throughout life and is regulated by pathological and physiological processes. The role of oxidative stress in hippocampal neurogenesis and its response to exercise or neurodegenerative diseases remains controversial. The present study was designed to investigate the impact of oxidative stress, treadmill exercise and sex on...

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Source

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Identifiers

PMID: 22558322
DOI: 10.1371/journal.pone.0036048
PMCID: PMC3338488

Genes

BDNF
IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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