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Article

Exercise-induced promotion of hippocampal cell proliferation requires beta-endorphin.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2008

Koehl M, Meerlo P, Gonzales D, Rontal A, Turek F W, Abrous D N

Abstract excerpt

Adult hippocampal neurogenesis is influenced by a variety of stimuli, including exercise, but the mechanisms by which running affects neurogenesis are not yet fully understood. Because beta-endorphin, which is released in response to exercise, increases cell proliferation in vitro, we hypothesized that it could exert a similar effect in vivo and mediate the stimulatory effects of running on neurogenesis. We thus...

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PMID: 18263701
DOI: 10.1096/fj.07-099101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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