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Article

Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of Alzheimer's Disease.

Brain pathology (Zurich, Switzerland) - 1 Jan 2016

Tapia-Rojas Cheril, Aranguiz Florencia, Varela-Nallar Lorena, Inestrosa Nibaldo C

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by loss of memory and cognitive abilities, and the appearance of amyloid plaques composed of the amyloid-β peptide (Aβ) and neurofibrillary tangles formed of tau protein. It has been suggested that exercise might ameliorate the disease; here, we evaluated the effect of voluntary running on several aspects of AD including amyloid deposition,...

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Identifiers

PMID: 25763997
DOI: 10.1111/bpa.12255
PMCID: PMC8029165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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