Article
Hippocampal neurogenesis is reduced by sleep fragmentation in the adult rat.
Neuroscience - 10 Aug 2007
Guzman-Marin R, Bashir T, Suntsova N, Szymusiak R, McGinty D
Abstract excerpt
The adult hippocampal dentate gyrus (DG) is a site of continuing neurogenesis. This process is influenced by a variety of physiological and experiential stimuli including total sleep deprivation (TSD). In humans, sleep fragmentation (SF) is a more common sleep condition than TSD. SF is associated with several prevalent diseases. We assessed a hypothesis that SF would suppress adult neurogenesis in the DG of the...
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