Article
Deciphering actin remodelling in immune cells through the prism of actin-related inborn errors of immunity.
European journal of cell biology - 1 Mar 2023
Dupré Loïc, Prunier Guilhèn
Abstract excerpt
Actin cytoskeleton remodelling drives cell motility, cell to cell contacts, as well as membrane and organelle dynamics. Those cellular activities operate at a particularly high pace in immune cells since these cells migrate through various tissues, interact with multiple cellular partners, ingest microorganisms and secrete effector molecules. The central and multifaceted role of actin cytoskeleton remodelling in...
Topics
- Humans
- Actins
- Actin Cytoskeleton
- Cell Movement
- Cytoskeletal Proteins
- Mutation
