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Article

Emerging functions of cytoskeletal proteins in immune diseases

1 Feb 2021

Abstract excerpt

Immune cells are especially dependent on the proper functioning of the actin cytoskeleton, and both innate and adaptive responses rely on it. Leukocytes need to adhere not only to substrates but also to cells in order to form synapses that pass on instructions or kill infected cells. Neutrophils literally squeeze their cell body during blood extravasation and efficiently migrate to the inflammatory focus....

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PMID: 33558442
DOI: 10.1242/jcs.253534

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