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Article

Ultrahigh-dimensional variable selection method for whole-genome gene-gene interaction analysis.

BMC bioinformatics - 3 May 2012

Ueki Masao, Tamiya Gen

Abstract excerpt

BACKGROUND: Genome-wide gene-gene interaction analysis using single nucleotide polymorphisms (SNPs) is an attractive way for identification of genetic components that confers susceptibility of human complex diseases. Individual hypothesis testing for SNP-SNP pairs as in common genome-wide association study (GWAS) however involves difficulty in setting overall p-value due to complicated correlation structure,...

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Identifiers

PMID: 22554139
DOI: 10.1186/1471-2105-13-72
PMCID: PMC3531267

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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