Article
TSGSIS: a high-dimensional grouped variable selection approach for detection of whole-genome SNP-SNP interactions.
Bioinformatics (Oxford, England) - 15 Nov 2017
Fang Yao-Hwei, Wang Jie-Huei, Hsiung Chao A
Abstract excerpt
MOTIVATION: Identification of single nucleotide polymorphism (SNP) interactions is an important and challenging topic in genome-wide association studies (GWAS). Many approaches have been applied to detecting whole-genome interactions. However, these approaches to interaction analysis tend to miss causal interaction effects when the individual marginal effects are uncorrelated to trait, while their interaction...
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