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Article

Lurcher Purkinje cells express glutamic acid decarboxylase and calbindin mRNAs.

Journal of neuroscience research - 1 Sept 1990

Wuenschell C W, Messer A, Tobin A J

Abstract excerpt

Purkinje neurons in immature Lurcher (Lc/+) mice are destined to die as a result of a defect intrinsic to the dying cells. We have used in situ hybridization to determine whether the Lc allele interferes with the normal program of gene expression in the doomed Purkinje cells. In P21 mice, degeneration of Purkinje cells is well underway, but the surviving Purkinje cells continue to express the mRNAs for both...

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PMID: 2254957
DOI: 10.1002/jnr.490270110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lurcher Purkinje cells express glutamic acid decarboxylase and calbindin mRNAs.PMID 2254957Read ↗

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