Article
Transplanted neurons alter the course of neurodegenerative disease in Lurcher mutant mice.
Experimental neurology - 1 Dec 1998
Heckroth J A, Hobart N J, Summers D
Abstract excerpt
Embryonic cerebellar, neocortical, and striatal tissues derived from NSE-LacZ transgenic mice were transplanted into the right cerebellar hemisphere of 8- to 10-day-old Lurcher or wild-type mice. Host mice survived for 30-90 days and the transplanted tissue was examined by light microscopy using Nissl staining, X-gal histochemistry, and immunohistochemistry for calcium binding protein and glutamic acid...
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