Article
Ionising irradiation alters the dynamics of human long interspersed nuclear elements 1 (LINE1) retrotransposon.
Mutagenesis - 1 Sept 2012
Tanaka Atsushi, Nakatani Youko, Hamada Nobuyuki, Jinno-Oue Atsushi, Shimizu Nobuaki, Wada Seiichi, Funayama Tomoo, Mori Takahisa, Islam Salequl, Hoque Sheikh Ariful, Shinagawa Masahiko, Ohtsuki Takahiro, Kobayashi Yasuhiko, Hoshino Hiroo
Abstract excerpt
It is important to identify the mechanism by which ionising irradiation induces various genomic alterations in the progeny of surviving cells. Ionising irradiation activates mobile elements like retrotransposons, although the mechanism of its phenomena consisting of transcriptions and insertions of the products into new sites of the genome remains unclear. In this study, we analysed the effects of sparsely...
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