Article
IL28B CC genotype is associated with higher all-cause mortality in antiretroviral-treated HIV-infected patients.
AIDS research and human retroviruses - 1 Dec 2012
Parczewski Miłosz, Bander Dorota, Leszczyszyn-Pynka Magdalena, Urbańska Anna, Socha Łukasz, Boroń-Kaczmarska Anna
Abstract excerpt
Il28B single nucleotide polymorphisms were found to influence interferon λ expression, resulting in changes in hepatitis C virus (HCV)-RNA serum levels as well as the HIV-RNA set point prior to combined antiretroviral therapy (cART). To date, there is limited information on the influence of this polymorphism on survival in HIV-infected, treatment-naïve, and antiretroviral-treated patients. Longitudinal data from...
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