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Article

Interleukin 28B rs12979860 genotype and Human Immunodeficiency Virus type 1: Susceptibility, AIDS development and therapeutic outcome.

Human immunology - 1 Jan 2018

Zaidane Imane, Wakrim Lahcen, Oulad Lahsen Ahd, Bensghir Rajaa, Chihab Hajar, Jadid Fatima Zahra, El Fihry Raouia, Lamdini Hassan, Fayssel Naouar, Marhoum El Filali Kamal, Oudghiri Mounia, Benjelloun Soumaya, Ezzikouri Sayeh

Abstract excerpt

Human Immunodeficiency Virus type 1 (HIV-1) infection and progression varies widely among individuals. Interferon-λ3 exerts anti-HIV function by activating JAK/STAT pathway-mediated innate immunity. Therefore, we aimed to investigate the association between single nucleotide polymorphisms of the interleukin 28B (IL28B) gene, and the risk of acquisition, AIDS development and therapeutic outcome of HIV-1 in a...

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Identifiers

PMID: 29080719
DOI: 10.1016/j.humimm.2017.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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