Article
IL28B polymorphism does not determine outcomes of hepatitis B virus or HIV infection.
The Journal of infectious diseases - 1 Dec 2010
Martin Maureen P, Qi Ying, Goedert James J, Hussain Shehnaz K, Kirk Gregory D, Hoots W Keith, Buchbinder Susan, Carrington Mary, Thio Chloe L
Abstract excerpt
An IL28B haplotype strongly determines the outcome of natural and interferon-α treated hepatitis C virus (HCV) infection. To assess whether the polymorphism marking the haplotype (rs12979860) also affects other interferon-α responsive chronic viral illnesses, namely hepatitis B virus (HBV) and human immunodeficiency virus (HIV) type 1 infections, we genotyped 226 individuals with HBV persistence, 384 with HBV...
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