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Article

Environmental induction of white-opaque switching in Candida albicans.

PLoS pathogens - 13 Jun 2008

Ramírez-Zavala Bernardo, Reuss Oliver, Park Yang-Nim, Ohlsen Knut, Morschhäuser Joachim

Abstract excerpt

Candida albicans strains that are homozygous at the mating type locus (MTLa or MTLalpha) can spontaneously switch at a low frequency from the normal yeast cell morphology (white) to an elongated cell type (opaque), which is the mating-competent form of the fungus. The ability to switch reversibly between these two cell types also contributes to the pathogenicity of C. albicans, as white and opaque cells are...

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Identifiers

PMID: 18551173
DOI: 10.1371/journal.ppat.1000089
PMCID: PMC2405950

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