Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Farnesoid X Receptor Induces Murine Scavenger Receptor Class B Type I via Intron Binding

23 Apr 2012

Abstract excerpt

Farnesoid X receptor (FXR) is a nuclear receptor and a key regulator of liver cholesterol and triglyceride homeostasis. Scavenger receptor class B type I (SR-BI) is critical for reverse cholesterol transport (RCT) by transporting high-density lipoprotein (HDL) into liver. FXR induces SR-BI, however, the underlying molecular mechanism of this induction is not known. The current study confirmed induction of SR-BI...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol and Lipid Metabolism
Share to Drug Transport and Resistance Mechanisms
Share to Peroxisome Proliferator-Activated Receptors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22540009
DOI: 10.1371/journal.pone.0035895

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Farnesoid X Receptor Induces Murine Scavenger Receptor Class B Type I via Intron BindingPMID 22540009Read ↗

Genome‐wide tissue‐specific farnesoid X receptor binding in mouse liver and intestine†Semantic proximity Read ↗

Influence of the HDL Receptor SR-BI on Lipoprotein Metabolism and AtherosclerosisSemantic proximity Read ↗

Structure and Localization of the Human Gene Encoding SR-BI/CLA-1Semantic proximity Read ↗

Functional genomics of the human high-density lipoprotein receptor scavenger receptor BI: an old dog with new tricks.Semantic proximity Read ↗

Liver X Receptors and their Agonists: Targeting for Cholesterol Homeostasis and Cardiovascular DiseasesSemantic proximity Read ↗

Scavenger Receptor class B type I (SR-BI): A versatile receptor with multiple functions and actionsSemantic proximity Read ↗

Alternative forms of the scavenger receptor BI (SR-BI).Semantic proximity Read ↗

Scavenger receptor class B type I is a plasma membrane cholesterol sensor.Semantic proximity Read ↗

The emerging roles of liver X receptors and their ligands in cancerSemantic proximity Read ↗

Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study.Semantic proximity Read ↗

Mechanistic insights into isoform-dependent and species-specific regulation of bile salt export pump by farnesoid X receptor.Semantic proximity Read ↗

Genome-Wide Binding and Transcriptome Analysis of Human Farnesoid X Receptor in Primary Human HepatocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.