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Article

Structure and Localization of the Human Gene Encoding SR-BI/CLA-1

1 Dec 1997

Abstract excerpt

The scavenger receptor, class B, type 1 receptor (SR-BI) mediates the selective transport of lipids from high density lipoprotein to cells. We describe the structure and subchromosomal location of human SR-BI and provide evidence that it is regulated by the transcription factor, steroidogenic factor 1 (SF-1). SR-BI resides on chromosome 12q24.2-qter, spans approximately 75 kilobase pairs, and contains 13 exons....

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Identifiers

PMID: 9407090
DOI: 10.1074/jbc.272.52.33068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structure and Localization of the Human Gene Encoding SR-BI/CLA-1PMID 9407090Read ↗

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Alternative forms of the scavenger receptor BI (SR-BI).Semantic proximity Read ↗

Impact of gene variants on sex-specific regulation of human Scavenger receptor class B type 1 (SR-BI) expression in liver and association with lipid levels in a population-based study.Semantic proximity Read ↗

Association of Polymorphisms at the SR-BI Gene Locus With Plasma Lipid Levels and Body Mass Index in a White PopulationSemantic proximity Read ↗

Genetic studies in mice and humans reveal new physiological roles for the high-density lipoprotein receptor scavenger receptor class B type I.Semantic proximity Read ↗

Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13Semantic proximity Read ↗

Scavenger receptor class B type I protein as an independent predictor of high-density lipoprotein cholesterol levels in subjects with hyperalphalipoproteinemia.Semantic proximity Read ↗

A synonymous variant in scavenger receptor, class B, type I gene is associated with lower SR-BI protein expression and function.Semantic proximity Read ↗

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease.Semantic proximity Read ↗

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