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Genome‐wide tissue‐specific farnesoid X receptor binding in mouse liver and intestine†

30 Nov 2009

Abstract excerpt

UNLABELLED: Farnesoid X receptor (FXR) is a bile acid-activated transcription factor belonging to the nuclear receptor superfamily. FXR is highly expressed in liver and intestine and crosstalk mediated by FXR in these two organs is critical in maintaining bile acid homeostasis. FXR deficiency has been implicated in many liver and intestine diseases. However, regulation of transcription by FXR at the genomic level...

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PMID: 20091679
DOI: 10.1002/hep.23450

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Genome‐wide tissue‐specific farnesoid X receptor binding in mouse liver and intestine†PMID 20091679Read ↗

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