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Article

Scavenger receptor class B type I is a plasma membrane cholesterol sensor.

Circulation research - 4 Jan 2013

Saddar Sonika, Carriere Véronique, Lee Wan-Ru, Tanigaki Keiji, Yuhanna Ivan S, Parathath Sajesh, Morel Etienne, Warrier Manya, Sawyer Janet K, Gerard Robert D, Temel Ryan E, Brown J Mark, Connelly Margery, Mineo Chieko, Shaul Philip W

Abstract excerpt

RATIONALE: Signal initiation by the high-density lipoprotein (HDL) receptor scavenger receptor class B, type I (SR-BI), which is important to actions of HDL on endothelium and other processes, requires cholesterol efflux and the C-terminal transmembrane domain. The C-terminal transmembrane domain uniquely interacts with plasma membrane (PM) cholesterol. OBJECTIVE: The molecular basis and functional significance...

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Share to Apolipoproteins B
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Nitric Oxide Synthase Type III

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Source

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Identifiers

PMID: 23023567
DOI: 10.1161/CIRCRESAHA.112.280081
PMCID: PMC3564583

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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