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Article

Rapid repetitive element-mediated expansion of piRNA clusters in mammalian evolution.

Proceedings of the National Academy of Sciences of the United States of America - 28 Apr 2009

Assis Raquel, Kondrashov Alexey S

Abstract excerpt

Piwi-interacting RNAs (piRNAs) are approximately 30 nucleotide noncoding RNAs that may be involved in transposon silencing in mammalian germline cells. Most piRNA sequences are found in a small number of genomic regions referred to as clusters, which range from 1 to hundreds of kilobases. We studied the evolution of 140 rodent piRNA clusters, 103 of which do not overlap protein-coding genes. Phylogenetic analysis...

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Identifiers

PMID: 19357307
DOI: 10.1073/pnas.0900523106
PMCID: PMC2667148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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