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Article

Polymorphisms of toll-like receptor 2 and 4 genes in Chagas disease.

Memorias do Instituto Oswaldo Cruz - 1 Feb 2008

Zafra German, Flórez Oscar, Morillo Carlos A, Echeverría Luis Eduardo, Martín Javier, González Clara Isabel

Abstract excerpt

The aim of this study was to test the possible implication of toll-like receptor 2 (TLR2) and TLR4 gene polymorphisms in determining the susceptibility to Chagas' disease. Genotypes were determined by polymerase chain reaction-restriction fragment length polymorphism in 475 individuals from Colombia, 143 seropositive with chagasic cardiomyopathy, 132 seropositive asymptomatic and 200 seronegative. The TLR2...

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Source

Identifiers

PMID: 18368233
DOI: 10.1590/s0074-02762008000100004

Genes

TLR2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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