Article
MicroRNA-mRNA interactions in a murine model of hyperoxia-induced bronchopulmonary dysplasia
30 May 2012
Abstract excerpt
BACKGROUND: Bronchopulmonary dysplasia is a chronic lung disease of premature neonates characterized by arrested pulmonary alveolar development. There is increasing evidence that microRNAs (miRNAs) regulate translation of messenger RNAs (mRNAs) during lung organogenesis. The potential role of miRNAs in the pathogenesis of BPD is unclear. RESULTS: Following exposure of neonatal mice to 80% O2 or room air (RA) for...
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