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Article

Pulmonary microRNA profiling in a mouse model of ventilator-induced lung injury

4 Jun 2012

Abstract excerpt

The aim of this study was to investigate the changes induced by high tidal volume ventilation (HVTV) in pulmonary expression of micro-RNAs (miRNAs) and identify potential target genes and corresponding miRNA-gene networks. Using a real-time RT-PCR-based array in RNA samples from lungs of mice subjected to HVTV for 1 or 4 h and control mice, we identified 65 miRNAs whose expression changed more than twofold upon...

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PMID: 22659882
DOI: 10.1152/ajplung.00370.2011

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