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Article

Loss of maternal CTCF is associated with peri-implantation lethality of Ctcf null embryos.

PloS one - 1 Jan 2012

Moore James M, Rabaia Natalia A, Smith Leslie E, Fagerlie Sara, Gurley Kay, Loukinov Dmitry, Disteche Christine M, Collins Steven J, Kemp Christopher J, Lobanenkov Victor V, Filippova Galina N

Abstract excerpt

CTCF is a highly conserved, multifunctional zinc finger protein involved in critical aspects of gene regulation including transcription regulation, chromatin insulation, genomic imprinting, X-chromosome inactivation, and higher order chromatin organization. Such multifunctional properties of CTCF suggest an essential role in development. Indeed, a previous report on maternal depletion of CTCF suggested that CTCF...

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Identifiers

PMID: 22532833
DOI: 10.1371/journal.pone.0034915
PMCID: PMC3332108

Genes

CTCF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Loss of maternal CTCF is associated with peri-implantation lethality of Ctcf null embryos.PMID 22532833Read ↗

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